Sudhir Joshi, Deepak Patel, Harish Chandra* and S.C. Bhatt
1Department of Physics
2Department of Chemistry
3Department of Medicinal and Aromatic Plants, HAPPRC
H. N. B. Garhwal University (A Central University), Srinagar, Garhwal-246174, Uttarakhand
Email: hreesh5@gmail.com
Received-02.10.2018, Revised-23.10.2018
Abstract: In the present study, the green method was used for the synthesis of zinc oxide nanoparticle from the dried leaves of Thymus vulgaris L. The synthesized ZnO NPs was characterized by UV-Vis spectrophotometer, XR Diffractometer, Scanning Electron Microscopy (SEM) and EDX (Energy Dispersive X-ray) spectrophotometer. The result suggests that the synthesized nanoparticles are crystalline in nature and in the nanorange. The average sizes of nanoparticle are 13.06 nm. The synthesized ZnO NPs was screened for the antibacterial activity against six pathogenic bacteria. Out of six bacterial strains tested, the ZnO NPs was found active against Salmonella typhi, Klebsiella pneumoniae, Staphylococcus aureus and Bacillus cereus but it does not have shown activity against E. coli and Enteococcus spp.
Keywords: Thymus vulgaris L., ZnO NPs, antibacterial activity
References
Saleh, H., Azizollah, J.K., Ahmadreza, H. and Raham, A. (2015). The Application of Thymus vulgaris in traditional and modern medicine: A Review. Global Journal of Pharmacology. 9 (3): 260-266.
Prasanth, R., Ravi, V.K., Varsha, P.V. and Satyam, S. (2014). Review on Thymus vulgaris traditional uses and pharmacological properties. Med Aromat Plants. 3 (4):1-3.
Safawoa, T., Sandeepa, B.V., Polaa, S. and Tadessec, A. (2018). Synthesis and characterization of zinc oxide nanoparticles using tuber extract of anchote (Coccinia abyssinica (Lam.) Cong.) for antimicrobial and antioxidant activity assessment. Open Nano. 3:56-63.
Chandra, H., Srivastava, J. and Agarwal, R.K. (2016): In: Fundamental Techniques in microbiology, Ist Edition, John Publisher Pvt. Ltd, New Delhi.
Boruga, O., Jianu, C., Mişcă, C., Goleţ, I., Gruia, A.T. and Horhat, F.G. (2014). Thymus vulgaris essential oil: chemical composition and antimicrobial activity. Journal of Medicine and Life. 7( 3): 56-60.
Chandra, H., Bishnoi, P., Yadav, A., Patni, B., Mishra, A. P. and Nautiyal, A.R. (2017). Antimicrobial Resistance and the Alternative Resources with Special Emphasis on Plant-Based Antimicrobials—A Review. Plants 6:16.
Srivastava, J. and Chandra, H. (2014). Antimicrobial resistance (AMR) and plant-derived antimicrobials (PDAms) as an alternative drug line to control infections. 3 Biotech. 4:451-460.